Success rate in In vitro fertilization – IVF

13/04/2022

In vitro fertilization (IVF) is a method of assisted reproduction by combining oocytes and sperm outside the body. The embryo formed after the oocyte and sperm are successfully combined will be transferred back to the woman’s uterus. The embryo then implants and develops into a fetus as in cases of natural conception. This is the most modern assisted reproductive method and is very popularly applied to infertile couples today.

Factors affecting the success rate of IVF

For infertile couples preparing to undergo assisted reproduction, the success rate of IVF is very important information, understanding these statistical ratios can help clients choose, make informed decisions before treatment .

The success rate of IVF depends on many factors, which include:

  • Causes of infertility: diseases, abnormalities of reproductive organs.
  • Wife age and infertility time: The older the wife, the longer the duration of infertility will reduce the success rate.
  • Medical and surgical diseases affecting reproductive function.
  • Embryo factor: Quantity and quality of embryo transferred
  • Habits of smoking, use of stimulants: may adversely affect treatment outcomes

However, not every cycle of treatment results in embryo transfer, and a small percentage of women have either no oocytes or immature oocytes after retrieval or have mature oocytes after retrieval but no fertilization to form an embryo resulting in no embryo to transfer.

Success rate after IVF treatment at Andrology and Fertility Hospital of Hanoi

Currently, 100% of the patients undergoing in vitro fertilization at the Andrology and Fertility Hospital of Hanoi are using ICSI (Intracytoplasmic Sperm Injection) technique to improve their fertility.

Post-treatment success rates are monitored, analyzed and reported periodically every six months. According to statistics from January 2023 to December 2023 are as follows:

Table 1: IVF success rate with female patients under 35 years old:

  Embryo transfer Embryo day 3 Embryo day 5
Total positive pregnancy tests/total pregnancy tests Fresh embryos 29 (41.4%) 38 (37.6%)
Cryopreservation embryos 171 (37%) 2384 (79%)
Clinical pregnancy rate Fresh embryos 19 (29.2%) 27 (27.6%)
Cryopreservation embryos 171 (39.5%) 1844 (66.1%)
Progressing pregnancy rate Fresh embryos 13 (21,7%) 23 (24.7%)
Cryopreservation embryos 127 (32.1%) 1423 (59%)

Ivf Success Rate With Female Patients Under 35 Years Old (3)

Ivf Success Rate With Female Patients Under 35 Years Old (2)

Ivf Success Rate With Female Patients Under 35 Years Old (1)

 

Table 2: IVF success rates with female patients aged 35-39 years:

  Embryo transfer Embryo day 3 Embryo day 5
Total positive pregnancy tests/total pregnancy tests Fresh embryos 4 (23.5%) 8 (40%)
Cryopreservation embryos 46 (45.5%) 258 (66.8%)
Clinical pregnancy rate Fresh embryos 1 (5.9%) 4 (22.2%)
Cryopreservation embryos 23 (24.7%) 193 (52.4%)
Progressing pregnancy rate Fresh embryos 1 (5.9%) 4 (22.2%)
Cryopreservation embryos 18 (20.5%) 146 (44.5)%

Ivf Success Rates With Female Patients Aged 35 39 Years (3)

Ivf Success Rates With Female Patients Aged 35 39 Years (2)

Ivf Success Rates With Female Patients Aged 35 39 Years (1)

Table 3: IVF success rate with female patients over 40 years old: (Women over the age of 40 years with an instruction for Preimplantation Genetic Testing – PGT before embryo transfer, this is the success rate when IVF/ICSI and PGT are combined):

  Embryo transfer Embryo day 3 Embryo day 5
Total positive pregnancy tests/total pregnancy tests Fresh embryos 1 (25%) 1 (20%)
Cryopreservation embryos 7 (25.9%) 47 (65.3)
Clinical pregnancy rate Fresh embryos
Cryopreservation embryos 5 (19.2%) 28 (40.6%)
Progressing pregnancy rate Fresh embryos
Cryopreservation embryos 3 (12.5%) 20 (31.8%)

  Ivf Success Rate With Female Patients Over 40 Years Old (3)

Ivf Success Rate With Female Patients Over 40 Years Old (2)

Ivf Success Rate With Female Patients Over 40 Years Old (1)

Table 4: Live birth rate in IVF by wife’s age and embryo age:

Wife’s age Embryo day 3 Embryo day 5
<35 years old 21/77 (27.3%) 198/308 (52.1%)
35-39 years old 2/13 (15.4%) 31/61 (50.8%)
>40 years old 1/8 (12.5%) 2/11 (18%)

Live Birth Rate In Ivf By Wife's Age And Embryo Age

At Andrology and Fertility Hospital of Hanoi, we are proud of the success rates we achieve when patients perform IVF at the hospital and are committed to improving IVF success rates by applying the latest technologies, promote research – continuous training of doctors – embryologists as well as individualization in patient care/treatment.

 


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